기초교실 - 교수진 소개
이경미 / Kyung-Mi Lee
- 세부전공세포 및 분자면역생화학
- 연구실위치문숙의학관 309호/미래융합기술관 318호
- 1987 서울대학교 약학대학 /학사 (약학전공)
- 1989 서울대학교 대학원 /석사 (물리약학전공)
- 1995 University of Chicago /박사 (약물학, 생리학전공)
- 교육 및 경력사항
- 1995-1996 Dept. of Pathology, Harvard Medical School ,Postdoctoral Fellow
- 1996-1999 Dept. of Immunology, University of Chicago ,Research Associate
- 2000-2001 Dept. of Immunology, University of Chicago ,Research Instructor
- 2001-2003 Dept. of Immunology, University of Chicago, Research Assistant Professor
- 2003-2006 고려대학교 의과대학 (조교수)
- 2006-2009 고려대학교 의과대학 (부교수)
- 2009-present 고려대학교 의과대학 (교수)
- 2013.01.01~2013.12.31 생화학 분자생물학회 (국제운영위원)
- 2012.01.01~2015.12.31 생화학 분자생물학회 (국제위원회 위원)
- 2007.01.01~2013.12.31 생화학 분자생물학회 (정회원)
- 2010.01.01~2011.12.31 생화학 분자생물학회 (일천위원)
- 2011.01.01~2011.12.31 생화학 분자생물학회 (포상위원)
- 2010.01.01~2010.12.31 생화학 분자생물학회 (학술운영위원)
- 2007.01.01~2009.12.31 생화학 분자생물학회 (대의원)
- 2008.01.02~2009.12.31 생화학 분자생물학회 (운영위원회 소식지 편집 운영위원)
- 2008.01.02~2009.12.31 생화학 분자생물학회 (학술위원)
- 2011.11.25~2012.10.11 DC 2012 (조직위원회 travel grant 위원)
- 2010.01.01~2011.12.31 대한면역학회 (운영위원 및 평의원)
- D.H. Lee, J. Ng, S. B. Kim, K. M. Lee*, and S. B. Han. 2014. Effect of donor age on the proportion of mesenchymal stem cells derived from anterior cruciate ligaments. 2015 Plos One. In press
T. C. Tu, N. K. Brown, T. J. Kim, X. Guo, X. Yang, H. S. Lee, V. Kumar, K. M. Lee*, and Y. X. Fu. 2014. CD160 is essential for NK-mediated IFN production. 2015. J Exp Med. Feb 23. pii: J Exp Med. 20131601. [Epub ahead of print]
T. J. Kim , V. Upadhyay, V. Kumar, K. M. Lee*, and Y. X. Fu. 2014. Innate lymphoid cells facilitate NK cell development through a lymphotoxin-mediated stromal microenvironment. J Exp Med. 30;211(7):1421-31.
T. J. Kim, M. Kim, H. M. Kim, S. A. Lim, E. Kim, K. Kim, K. H. Song, V. Kumar, C. Yee, J. Doh and K. M. Lee*. 2014. Homotypic NK cell-to-cell communication controls cytokine responsiveness of innate immune NK cells. Scientific Reports. 2014 Sci Rep. Dec 5;4:7157. doi: 10.1038/srep07157..
S. W. Hwang., G. Park, C. Edwards, E. Corbin, S. Kang, H. Cheng, J. Song, J. H. Kim, S. Y. Yu, B. Bhaduri, F. Omenetto, Y. Huang, L. Goddard, G. Popescu, K. M. Lee*, and J. A. Rogers 2014. Chemistry and Biocompatibility of Single Crystalline Silicon Nanomembranes and Associated Materials for Transient Electronics. ACS Nano. 24;8(6):5843-51.
S. W. Hwang., G. Park, H. Cheng, J. K. Song, S. K. Kang, L Yin, J. H. Kim, F. G. Omennetto, Y. Huang, K. M. Lee*, and J. A. Rogers. 2014. Materials for high performance biodegradable semiconductor devices. Adv Mater. 2;26(13):1992-2000.
K. H. Noh., S. H. Kim, J. H. Kim, K. H. Song, K. Kim, Y. H. Lee,T. H. Kang, H. D. Han, A. K. Sood, J. Ng, C. H. Sonn, V. Kumar, C. Yee, K. M. Lee.* and T. W. Kim. 2014. API5 drives tumor immune resistance through an FGF2/FGFR1/PKCδ/ERK-dependent cell survival pathway. Cancer Res. 74(13):3556-66.
J. E. Lee., S. A. Lim, T. J. Kim, K. Kim, J. Ng, Y. H. Kim, I. J. Jang, S. B. Oh, J. C. Lee, C. Yee, V. Kumar and K. M. Lee.* 2014. NKG2D ligation relieves 2B4-mediated NK cell self-tolerance in mice. Eur J Immunol. 44(6):1802-13
B. Park, C. Yee, K. M. Lee*. 2014. The effect of radiation on the immune response to cancers. Int J Mol Sci 10;15(1):927-43
Han D, Kim HJ, Choi HY, Kim BW, Yang G, Han J, Dayem AA, Lee HR, Kim JH, Lee KM, Jeong KS, Do SH, Cho SG. 3,2′-Dihydroxyflavone-treated Pluripotent Stem Cells Show Enhanced Proliferation, Pluripotency Markers , and Neuroprotective Properties. Cell Transplantation. Cell Transplant. 2014 Jul 30. [Epub ahead of print]
H. Saito, S. Ando, N. Morishita, K.M. Lee, D. Dator, D. Dy, K. Shigemura, Z. Adhim, K. Nibu, M. Fujisawa and T. Shirakawa. 2014. A Combined Lymphokine-activated Killer (LAK) Cell Immunotherapy and Adenovirus-p53 Gene Therapy for Head and Neck Squamous Cell Carcinoma. Anticancer Res. 34(7):3365-70.
G. Park., H. J. Chung, K. Kim, S. A. Lim, J. Kim, Y. S. Kim, Y. Liu, W. H. Yeo, R. H. Kim, S. S. Kim, J. S. Kim, Y. H. Jung, T. i. Kim, C. Yee, J. A. Rogers, and K. M. Lee*. 2013. Immunologic and Tissue Biocompatibility of Flexible/Stretchable Electronics and Optoelectronics. Advanced Healthcare Materials. Accepted
K. Lee., V. Nguyen, K. M. Lee, S. M. Kang, and Q. Tang. 2013. Reduction of donor-reactive T cells is a prerequisite for effective control of allograft rejection using regulatory T cell therapy. American Journal of Transplantation. Accepted
Lee, D. H., J. Ng, J. W. Chung, C. H. Sonn, K. M. Lee* and S. B. Han. 2013. The Impact of Chronicity of Injury on the Proportion of Mesenchymal Stem Cells Derived from Anterior Cruciate Ligaments. Cytotherapy. Accepted
Bong, J. J., Y. M. Kang, S. C. Shin, S. J. Choi, K. M. Lee*, and H. S. Kim. 2013. Differential e-pression of thymic DNA repair genes in low-dose-rate irradiated AKR/J mice. Journal of Veterinary Science. in print
Bong, J. J., Y. M. Kang, S. C. Shin, S. J. Choi, K. M. Lee*, and H. S. Kim. 2013. Identification of radiation-sensitive expressed genes in the ICR and AKR/J mouse thymus. Cell Biol Int 37: 485-494.
Lim, S. A., T. J. Kim, J. E. Lee, C. H. Sonn, K. Kim, J. Kim, J. G. Choi, I. K. Choi, C. O. Yun, J. H. Kim, C. Yee, V. Kumar, and K. M. Lee*. 2013. Ex vivo expansion of highly cytotoxic human NK cells by cocultivation with irradiated tumor cells for adoptive immunotherapy. Cancer Res 73: 2598-2607.
Kim, K., H. J. An, S. H. Jun, T. J. Kim, S. A. Lim, G. Park, H. B. Na, Y. I. Park, T. Hyeon, C. Yee, J. A. Bluestone, J. Kim, and K. M. Lee.* 2012. Single step isolation and activation of primary CD3+ T lymphocytes using alcohol-dispersed electrospun magnetic nanofibers. Nano Lett 12: 4018-4024.
Jun, S. H., K. Kim, H. J. An, B. C. Kim, C. H. Sonn, M. Kim, J. Doh, C. Yee, K. M. Lee,* and J. Kim. 2012. Ethanol-Dispersed Polymer Nanofibers as a Highly Selective Cell Isolation and Release Platform for CD4(+) T Lymphocytes. Adv Funct Mater 22: 4448-4455.
Sonn, C. H., J. R. Choi, T. J. Kim, Y. B. Yu, K. Kim, S. C. Shin, G. H. Park, T. Shirakawa, H. S. Kim, and K. M. Lee.* 2012. Augmentation of natural cytotoxicity by chronic low-dose ionizing radiation in murine natural killer cells primed by IL-2. J Radiat Res 53: 823-829.
Hong, Y. J., N. Kim, K. Lee, C. Hee Sonn, J. Eun Lee, S. Tae Kim, I. Ho Baeg, and K. M. Lee.* 2012. Korean red ginseng (Panax ginseng) ameliorates type 1 diabetes and restores immune cell compartments. J Ethnopharmacol 144: 225-233.
Lee, D. H., C. H. Sonn, S. B. Han, Y. Oh, K. M. Lee*, and S. H. Lee. 2012. Synovial fluid CD34(-) CD44(+) CD90(+) mesenchymal stem cell levels are associated with the severity of primary knee osteoarthritis. Osteoarthritis Cartilage 20: 106-109.
Jung, G. A., B. S. Shin, Y. S. Jang, J. B. Sohn, S. R. Woo, J. E. Kim, G. Choi, K. M. Lee, B. H. Min, K. H. Lee, and G. H. Park. 2011. Methylation of eukaryotic elongation factor 2 induced by basic fibroblast growth factor via mitogen-activated protein kinase. Exp Mol Med 43: 550-560.
Shim, Y. J., B. H. Kang, H. S. Jeon, I. S. Park, K. U. Lee, I. K. Lee, G. H. Park, K. M. Lee, P. Schedin, and B. H. Min. 2011. Clusterin induces matrix metalloproteinase-9 expression via ERK1/2 and PI3K/Akt/NF-kappaB pathways in monocytes/macrophages. J Leukoc Biol 90: 761-769.
Won, Y. W., S. M. Yoon, C. H. Sonn, K. M. Lee*, and Y. H. Kim. 2011. Nano self-assembly of recombinant human gelatin conjugated with alpha-tocopheryl succinate for Hsp90 inhibitor, 17-AAG, delivery. ACS Nano 5: 3839-3848.
Lee, J. C., K. M. Lee, Y. O. Ahn, B. Suh, and D. S. Heo. 2011. A possible mechanism of impaired NK cytotoxicity in cancer patients: down-regulation of DAP10 by TGF-beta1. Tumori 97: 350-357.
An, H. J., H. J. Lee, S. H. Jun, S. Y. Hwang, B. C. Kim, K. Kim, K. M. Lee, M. K. Oh, and J. Kim. 2011. Enzyme precipitate coatings of lipase on polymer nanofibers. Bioprocess Biosyst Eng 34: 841-847.
Saito, A., N. Morishita, C. Mitsuoka, S. Kitajima, K. Hamada, K. M. Lee, M. Kawabata, M. Fujisawa, and T. Shirakawa. 2011. Intravenous injection of irradiated tumor cell vaccine carrying oncolytic adenovirus suppressed the growth of multiple lung tumors in a mouse squamous cell carcinoma model. J Gene Med 13: 353-361.
Adhim, Z., T. Matsuoka, T. Bito, K. Shigemura, K. M. Lee, M. Kawabata, M. Fujisawa, K. Nibu, and T. Shirakawa. 2011. In vitro and in vivo inhibitory effect of three Cox-2 inhibitors and epithelial-to-mesenchymal transition in human bladder cancer cell lines. Br J Cancer 105: 393-402.
Choi, I. K., J. S. Lee, S. N. Zhang, J. Park, C. H. Sonn, K. M. Lee, and C. O. Yun. 2011. Oncolytic adenovirus co-expressing IL-12 and IL-18 improves tumor-specific immunity via differentiation of T cells expressing IL-12Rbeta2 or IL-18Ralpha. Gene Ther 18: 898-909.
Min, J. H., S. T. Kim, J. S. Lee, K. Kim, J. H. Wu, J. Jeong, A. Y. Song, K. M. Lee*, and Y. K. Kim. 2011. Labeling of macrophage cell using biocompatible magnetic nanoparticles. J Appl Phys 109.
Park, S. Y., W. K. Jeong, M. J. Kim, K. M. Lee, W. S. Lee, and D. H. Lee. 2010. Necrotising fasciitis in both calves caused by Aeromonas caviae following aesthetic liposuction. J Plast Reconstr Aes 63: E695-E698.
Shin, S. C., K. M. Lee*, Y. M. Kang, K. Kim, S. A. Lim, K. H. Yang, J. Y. Kim, S. Y. Nam, and H. S. Kim. 2011. Differential expression of immune-associated cancer regulatory genes in low- versus high-dose-rate irradiated AKR/J mice. Genomics 97: 358-363.
Won, Y. W., S. M. Yoon, K. M. Lee, and Y. H. Kim. 2011. Poly(oligo-D-arginine) With Internal Disulfide Linkages as a Cytoplasm-sensitive Carrier for siRNA Delivery. Molecular Therapy 19: 372-380.
Lee, D. H., S. D. Joo, S. B. Han, J. Im, S. H. Lee, C. H. Sonn, and K. M. Lee*. 2011. Isolation and expansion of synovial CD34(-)CD44(+)CD90(+) mesenchymal stem cells: comparison of an enzymatic method and a direct explant technique. Connect Tissue Res 52: 226-234.
Kim, J. H., T. H. Kang, K. H. Noh, S. H. Kim, Y. H. Lee, K. W. Kim, H. C. Bae, Y. H. Ahn, E. Y. Choi, J. S. Kim, K. M. Lee, and T. W. Kim. 2010. Enhancement of DC vaccine potency by activating the PI3K/AKT pathway with a small interfering RNA targeting PTEN. Immunol Lett 134: 47-54.
Kim, E. O., T. J. Kim, N. Kim, S. T. Kim, V. Kumar, and K. M. Lee*. 2010. Homotypic cell to cell cross-talk among human natural killer cells reveals differential and overlapping roles of 2B4 and CD2. J Biol Chem 285: 41755-41764.
Yamamoto, S., J. Wada, T. Katayama, T. Jikimoto, M. Nakamura, S. Kinoshita, K. M. Lee, M. Kawabata, and T. Shirakawa. 2010. Genetically modified Bifidobacterium displaying Salmonella-antigen protects mice from lethal challenge of Salmonella Typhimurium in a murine typhoid fever model. Vaccine 28: 6684-6691.
Hong, S. J., S. T. Kim, T. J. Kim, E. O. Kim, C. M. Ahn, J. H. Park, J. S. Kim, K. M. Lee*, and D. S. Lim. 2010. Cellular and molecular changes associated with inhibitory effect of pioglitazone on neointimal growth in patients with type 2 diabetes after zotarolimus-eluting stent implantation. Arterioscler Thromb Vasc Biol 30: 2655-2665.
Kim, S. T., D. J. Kim, T. J. Kim, D. W. Seo, T. H. Kim, S. Y. Lee, K. Kim, K. M. Lee*, and S. K. Lee. 2010. Novel streptavidin-functionalized silicon nanowire arrays for CD4+ T lymphocyte separation. Nano Lett 10: 2877-2883.
Kim, T. J., N. Kim, H. J. Kang, E. O. Kim, S. T. Kim, H. S. Ahn, J. A. Bluestone, and K. M. Lee*. 2010. FK506 causes cellular and functional defects in human natural killer cells. J Leukoc Biol 88: 1089-1097.
Kim, E. O., N. Kim, T. J. Kim, K. Kim, T. W. Kim, V. Kumar, and K. M. Lee*. 2010. Unidirectional signaling triggered through 2B4 (CD244), not CD48, in murine NK cells. J Leukoc Biol 88: 707-714.
Sonn, C. H., Y. B. Yu, Y. J. Hong, Y. J. Shim, J. A. Bluestone, B. H. Min, and K. M. Lee*. 2010. Clusterin synergizes with IL-2 for the expansion and IFN-gamma production of natural killer cells. J Leukoc Biol 88: 955-963.
Kim, E. Y., J. M. Seo, C. Kim, J. E. Lee, K. M. Lee, and J. H. Kim. 2010. BLT2 promotes the invasion and metastasis of aggressive bladder cancer cells through a reactive oxygen species-linked pathway. Free Radic Biol Med 49: 1072-1081.
Shin, S. C., K. M. Lee*, Y. M. Kang, K. Kim, C. S. Kim, K. H. Yang, Y. W. Jin, and H. S. Kim. 2010. Alteration of cytokine profiles in mice exposed to chronic low-dose ionizing radiation. Biochem Biophys Res Commun 397: 644-649.
Kim, T. J., N. Kim, E. O. Kim, J. R. Choi, J. A. Bluestone, and K. M. Lee*. 2010. Suppression of human anti-porcine natural killer cell xenogeneic responses by combinations of monoclonal antibodies specific to CD2 and NKG2D and extracellular signal-regulated kinase kinase inhibitor. Immunology 130: 545-555.
Lee, S. Y., G. R. Choi, H. Lim, K. M. Lee, and S. K. Lee. 2009. Electronic transport characteristics of electrolyte-gated conducting polyaniline nanowire field-effect transistors (vol 95, 013113, 2009). Appl Phys Lett 95.
K. M. Lee,., and S. Y. Seong. 2009. Partial role of TLR4 as a receptor responding to damage-associated molecular pattern. Immunol Lett 125: 31-39.
Son, S. W., E. O. Kim, E. S. Ryu, T. J. Kim, J. N. Kim, J. E. Choi, Y. C. Kye, and K. M. Lee*. 2009. Upregulation of Fas and downregulation of CD94/NKG2A inhibitory receptors on circulating natural killer cells in patients with new-onset psoriasis. Br J Dermatol 161: 281-288.
Kim, S. T., D. J. Jang, J. H. Kim, J. Y. Park, J. S. Lim, S. Y. Lee, K. M. Lee, S. J. Lim, and C. K. Kim. 2009. Topical administration of cyclosporin A in a solid lipid nanoparticle formulation. Pharmazie 64: 510-514.
Kim, S. T., K. M. Lee, H. J. Park, S. E. Jin, W. S. Ahn, and C. K. Kim. 2009. Topical delivery of interleukin-13 antisense oligonucleotides with cationic elastic liposome for the treatment of atopic dermatitis. J Gene Med 11: 26-37.
Liu, H. L., C. H. Sonn, J. H. Wu, K. M. Lee*, and Y. K. Kim. 2008. Synthesis of streptavidin-FITC-conjugated core-shell Fe3O4-Au nanocrystals and their application for the purification of CD4+ lymphocytes. Biomaterials 29: 4003-4011.
Jeong, J., K. Juhn, H. Lee, S. H. Kim, B. H. Min, K. M. Lee, M. H. Cho, G. H. Park, and K. H. Lee. 2007. SIRT1 promotes DNA repair activity and deacetylation of Ku70. Exp Mol Med 39: 8-13.
K. M Lee,., Son S. W., G. Babnigg, and M. L. Villereal. 2006. Tyrosine phosphatase and cytochrome P450 activity are critical in regulating store-operated calcium channels in human fibroblasts. Exp Mol Med 38: 703-717.
Ju, Y. J., K. H. Lee, J. E. Park, Y. S. Yi, M. Y. Yun, Y. H. Ham, T. J. Kim, H. M. Choi, G. J. Han, J. H. Lee, J. Lee, J. S. Han, K. M. Lee*, and G. H. Park. 2006. Decreased expression of DNA repair proteins Ku70 and Mre11 is associated with aging and may contribute to the cellular senescence. Exp Mol Med 38: 686-693.
K. M. Lee., J. P. Forman, M. E. McNerney, S. Stepp, S. Kuppireddi, D. Guzior, Y. E. Latchman, M. H. Sayegh, H. Yagita, C. K. Park, S. B. Oh, C. Wulfing, J. Schatzle, P. A. Mathew, A. H. Sharpe, and V. Kumar. 2006. Requirement of homotypic NK-cell interactions through 2B4(CD244)/CD48 in the generation of NK effector functions. Blood 107: 3181-3188.
McNerney, M. E., K. M. Lee (co-first), P. Zhou, L. Molinero, M. Mashayekhi, D. Guzior, H. Sattar, S. Kuppireddi, C. R. Wang, V. Kumar, and M. L. Alegre. 2006. Role of natural killer cell subsets in cardiac allograft rejection. Am J Transplant 6: 505-513.
Seong, J. H., K. M. Lee, S. T. Kim, S. E. Jin, and C. K. Kim. 2006. Polyethylenimine-based antisense oligodeoxynucleotides of IL-4 suppress the production of IL-4 in a murine model of airway inflammation. J Gene Med 8: 314-323.
McNerney, M. E., K. M. Lee, and V. Kumar. 2005. 2B4 (CD244) is a non-MHC binding receptor with multiple functions on natural killer cells and CD8+ T cells. Mol Immunol 42: 489-494 .
Vaidya, S. V., S. E. Stepp, M. E. McNerney, J. K. Lee, M. Bennett, K. M. Lee, C. L. Stewart, V. Kumar, and P. A. Mathew. 2005. Targeted disruption of the 2B4 gene in mice reveals an in vivo role of 2B4 (CD244) in the rejection of B16 melanoma cells. J Immunol 174: 800-807.
Lee, K., K. M. Lee, T. J. Kim, M. K. Kim, J. S. Han, Y. S. Hong, G. H. Park, and K. W. Lee. 2004. The nuclear 16-kD protein methylation increases in the early period of liver regeneration in a hepatectomized rat. Exp Mol Med 36: 563-571.
Yeon, K. Y., M. Y. Sim, S. Y. Choi, S. J. Lee, K. Park, J. S. Kim, J. H. Lee, K. M. Lee*, and S. B. Oh. 2004. Molecular mechanisms underlying calcium current modulation by nociceptin. Neuroreport 15: 2205-2209.
Karandikar, N. J., S. H. Kroft, S. Yegappan, B. B. Rogers, V. M. Aquino, K. M. Lee, V. Kumar, F. J. Guenaga, E. S. Jaffe, D. C. Douek, and R. W. McKenna. 2004. Unusual immunophenotype of CD8+ T cells in familial hemophagocytic lymphohistiocytosis. Blood 104: 2007-2009.
Lee, J. C., K. M. Lee, D. W. Kim, and D. S. Heo. 2004. Elevated TGF-beta1 secretion and down-modulation of NKG2D underlies impaired NK cytotoxicity in cancer patients. J Immunol 172: 7335-7340.
Lee, K. M., M. E. McNerney, S. E. Stepp, P. A. Mathew, J. D. Schatzle, M. Bennett, and V. Kumar. 2004. 2B4 acts as a non-major histocompatibility complex binding inhibitory receptor on mouse natural killer cells. J Exp Med 199: 1245-1254.
Kwon, S. Y., S. Kim, K. Lee, T. J. Kim, S. H. Lee, K. M. Lee, and G. H. Park. 2004. Increased methylation of the cytosolic 20-kD protein is accompanied by liver regeneration in a hepatectomized rat. Exp Mol Med 36: 85-92.
Lee, K. M*(., S. Bhawan, T. Majima, H. Wei, M. I. Nishimura, H. Yagita, and V. Kumar. 2003. Cutting edge: the NK cell receptor 2B4 augments antigen-specific T cell cytotoxicity through CD48 ligation on neighboring T cells. J Immunol 170: 4881-4885.
Park, C. G., N. W. Thiex, K. M. Lee, G. L. Szot, J. A. Bluestone, and K. D. Lee. 2003. Targeting and blocking B7 costimulatory molecules on antigen-presenting cells using CTLA4Ig-conjugated liposomes: in vitro characterization and in vivo factors affecting biodistribution. Pharm Res 20: 1239-1248.
Lee, K. M. 2002. Identification of SAP as a CTLA-4 Binding Molecule: a Role of SAP in CTLA-4 Signaling Proposed. Immune Netw 2: 72-78.
Lee, K. M. 2001. T cell costimulation by CD28, CTLA-4, and ICOS. Immune Netw 1: 95-103.
Griffin, M. D., D. K. Hong, P. O. Holman, K. M. Lee, M. J. Whitters, S. M. O’Herrin, F. Fallarino, M. Collins, D. M. Segal, and T. F. Gajewski. 2000. Blockade of T cell activation using a surface-linked single-chain antibody to CTLA-4 (CD152). The Journal of Immunology 164: 4433-4442.
Chuang, E., K. M. Lee (co-first), M. D. Robbins, J. M. Duerr, M. L. Alegre, J. E. Hambor, M. J. Neveu, J. A. Bluestone, and C. B. Thompson. 1999. Regulation of cytotoxic T lymphocyte-associated molecule-4 by Src kinases. J Immunol 162: 1270-1277.
K. M. Lee.(co-first)., E. Chuang, M. Griffin, R. Khattri, D. K. Hong, W. Zhang, D. Straus, L. E. Samelson, C. B. Thompson, and J. A. Bluestone. 1998. Molecular basis of T cell inactivation by CTLA-4. Science 282: 2263-2266.
K. M. Lee., K. Y. Tsai, N. Wang, and D. E. Ingber. 1998. Extracellular matrix and pulmonary hypertension: control of vascular smooth muscle cell contractility. Am J Physiol 274: H76-82.
K. M. Lee.., and M. L. Villereal. 1996. Tyrosine phosphorylation and activation of pp60c-src and pp125FAK in bradykinin-stimulated fibroblasts. Am J Physiol 270: C1430-1437.
K. M. Lee.,., K. Toscas, and M. L. Villereal. 1993. Inhibition of bradykinin- and thapsigargin-induced Ca2+ entry by tyrosine kinase inhibitors. J Biol Chem 268: 9945-9948.
Chao, T. S., K. L. Byron, K. M. Lee.,, M. Villereal, and M. R. Rosner. 1992. Activation of MAP kinases by calcium-dependent and calcium-independent pathways. Stimulation by thapsigargin and epidermal growth factor. J Biol Chem 267: 19876-19883.
Kim, C..K., K. M. Lee.,, S..J. Hwang, and Y.-S. Yoon. 1990. Preparation of substained-release microspheres of phenylpropanolamine HCl and their release characteristics. Arch Pharm Res 13: 293-297.
- 기타사항(특허, 저서, fellowship, Awards 등)
- memberships and honors
1985-1987 Seoul National University, Departmental Honors
1989-1994 University of Chicago, Erma Smith Fellowship
1995 Charles Higgins Award for Physiologists
2008 Ilcheon Young Scientist Award
2011 EMM Journal Achievement Award
2012 동아일보 “10년 뒤 한국을 빛낼 100인” 선정