기초교실 - 교수진 소개

박윤규 교수

박윤규 교수

박윤규 / Yun-Gyu Park

  • 소속생화학분자생물학교실
  • 직위교수
  • 세부전공종양생화학
  • 연구실위치문숙의학관 316호
  • 구내전화번호02-2286-1183
  • 팩스02-923-0480
  • 이메일parkyg@korea.ac.kr
학력사항
1981.03-1987.02 고려대학교 의과대학 의학사
1987.03-1989.02 고려대학교 대학원 의학석사 (생화학전공)
1989.03-1992.02 고려대학교 대학원 의학박사 (생화학전공)
교육 및 경력사항
1996.01-1999.04 미국립보건원 국립암연구소 종양면역생물학실험실 박사후연구원
1999.03-현재 고려대학교 의과대학 생화학분자생물학교실 조교수, 부교수, 교수
2006.03-2007.02 Stanford University, Department of Medicine (Oncology) & Stanford Institute for Stem Cell Biology and Regenerative Medicine, Visiting Associate Professor
2008.02-2009.02 고려대학교 의과대학 연구교류부학장
2008.02-2009.02 고려대학교 의무산학협력실장
2009.03-2010.02 고려대학교 의과학연구지원센터장
2009.03-2013.02 고려대학교 한국분자의학영양연구소장
2009.08-2013.07 고려대학교 의과대학 생화학교실 주임교수
2011.05-2013.04 고려대학교 교수입학사정관
2013.05-2015.05 보건의료기술정책심의위원회 평가관리 전문위원회1(중개연구분야) (위원)
2014.10-2015.05 보건의료기술정책심의위원회 평가관리 전문위원회1(중개연구분야) (위원장)
학술활동
1999 ~ 현재 생화화분자생물학회(구, 대한생화학분자생물학회), 정회원
2001 ~ 현재 미국암학회, 정회원
2004.01-2005.12 생화학분자생물학회 운영위원회(홍보/회원 운영위원)
2004.01-2004.12 생화학분자생물학회 학술정보위원회 (위원)
2010.01-2010.12 생화학분자생물학회 출판위원회 (위원)
2008 ~ 현재 생화학분자생물학회 (대의원)
2015.01-2015.12 생화학분자생물학회 선거위원회 (위원장)
2015.01-2015.12 생화학분자생물학회 윤리위원회 (위원)
대표논문
< 학술지 >
Kim CS, Lee KJ, Kim JE, Park YG, Ryu JJ, Kim HR: Proteomic analysis of the biological response of MG63 osteoblast-like cells to titanium implants. Odontology 102(2):241-8, 2014

Kim Y, Kim HD, Youn B, Park YG, Kim J: Ribosomal protein S3 is secreted as a homodimer in cancer cells. Biochem Biophys Res Commun 441(4):805-8, 2013

Kim HD, Yu SJ, Kim HS, Kim YJ, Choe JM, Park YG, Kim J, Sohn J: IL-4 induces senescence in human renal carcinoma cell lines through STAT6 and p38 MAPK. J Biol Chem 288(40):28743-54, 2013

An S, Yun M, Park YG, Park GH: Proteomic Identification of Cytosolic Proteins that Undergo Arginine Methylation during Rat Liver Regeneration. Electrophoresis 30(14):2412-2421, 2009

Park YG: Inhibition of hepatitis B virus replication by RNA interference. Korean J Hepatol 15(1):1-6, 2009

Kim JE, Koo KH, Kim YH, Sohn J, Park YG: Identification of potential lung cancer biomarkers using in vitro carcinogenesis model. Exp Mol Med 40(6):709-720, 2008

Song HK, Lee MH, Kim BK, Park YG, Ko GJ, Kang YS, Han JY, Han SY, Han KH, Kim HK, Cha DR.: Visfatin: A New Player in Mesangial Cell Physiology and Diabetic Nephropathy. Am J Physiol Renal Physiol. 295(5): F1485 F1494, 2008

Kim BK, Lim SO, Park YG: Requirement of the cyclic adenosine monophosphate response element binding protein for Hepatitis B virus replication. Hepatology 48(2):361-373, 2008

Lee JY, Yu SJ, Park YG, Kim J, Sohn J.: Glycogen synthase kinase 3 beta phosphorylates p21(WAF1/CIP1) for proteasomal degradation after UV irradiation. Mol Cell Biol. 27(8): 3187-3198, 2007

Kang YS, Park YG, Kim BK, Han SY, Jee YH, Han KH, Lee MH, Song HK, Cha DR, Kang SW, Han DS: Angiotensin II stimulates the synthesis of vascular endothelial growth factor through the p38 mitogen activated protein kinase pathway in cultured mouse podocytes. J Mol Endocrinol. 36(2):377-388 2006

Kim MJ, Kang JH, Park YG, Ryu GR, Ko SH, Jeong IK, Koh KH, Rhie DJ, Yoon SH, Hahn SJ, Kim MS, Jo YH: Exendin-4 induction of cyclin D1 expression in INS-1 b-cells: involvement of cAMP-responsive element. J Endocrinol. 188(3):623-633, 2006

Cho YS, Kim MK, Cheadle C, Neary C, Park YG, Becker KG, Cho-Chung YS: A genomic-scale view of the cAMP response element-enhancer decoy: A tumor targetbased genetic tool. Proc. Natl. Acad. Sci. USA 99(24):15626-15631, 2002
Choi DH, Kim DH, Park YG, Chun BG, Choi SH: Protective effects of rilmenidine and AGN 192403 on oxidative cytotoxicity and mitochondrial inhibitor-induced cytotoxicity in astrocytes. Free Radic Biol Med. 33(10):1321-1333, 2002

Park GH, Choe J, Choo HJ, Park YG, Sohn J, and Kim MK: Genome-wide expression of profiling of 8-chloroadenosine- and 8-chloro-cAMP-treated human neuroblastoma cells using radioactive human cDNA microarray. Exp Mol Med 34(3):184-193, 2002

Cho-Chung YS, Nesterova M, Becker KG, Srivastava R, Park YG, Lee YN, Cho YS, Kim MK, Neary C, and Cheadle C: Dissecting the circuitry of Protein Kinase A and cAMP signaling in cancer genesis: antisense, microarray, gene overexpression, and transcription factor decoy. Ann N Y Acad Sci 968:22-36, 2002

Park YG, Park S, Lim SO, Lee MS, Ryu CK, Kim IS, and Cho-Chung YS: Reduction in Cyclin D1/Cdk4/Retinoblastoma Protein Signaling by CRE-Decoy Oligonucleotide. Biochem Biophys Res Commun 281(5):1213-1219, 2001

Cho-Chung YS, Park YG, Nesterova M, Lee YN, and Cho YS: CRE-decoy oligonucleotide-inhibition of gene expression and tumor growth. Mol Cell Biochem 212(1-2):29-34, 2000

Nesterova M, Noguchi K, Park YG, Lee YN, and Cho-Chung YS: Compensatory Stabilization of RII Protein, Cell Cycle Deregulation, and Growth Arrest in Colon and Prostate Carcinoma Cells by Antisense-directed Down-Regulation of Protein Kinase A RI Protein. Clin Cancer Res 6(9):3434-3441, 2000

Lee YN, Park YG, Choi YH, Cho YS, and Cho-Chung YS: CRE-Transcription Factor Decoy Oligonucleotide Inhibition of MCF-7 Breast Cancer Cells: Cross-Talk with p53 Signaling Pathway. Biochemistry 39(16):4863-4868, 2000

Cho YS, Park YG, Lee YN, Kim MK, Bates S, Tan L, and Cho-Chung YS: Extracellular protein kinase A as a cancer biomarker: Its expression by tumor cells and reversal by a myristate-lacking Ca and RIIb subunit overexpression. Proc. Natl. Acad. Sci. USA 97(2):835-840, 2000

Cho-Chung YS, Nesterova M, Pepe S, Lee GR, Noguchi K, Srivastava RK, Srivastava AR, Alper O, Park YG, and Lee YN: Antisense DNA-targeting protein kinase A-RIa subunit: A novel approach to cancer treatment. Front Biosci. 4: D898-907, 1999

Cho-Chung YS, Nesterova M, Park YG, and Lee YN: Protein kinase A-RIa antisense: Antitumor mechanism of action. Antisense & Nucleic Acid Drug Devel. 9(4): 383-388, 1999

Cho-Chung YS, Park YG, and Lee YN: Oligonucleotides as transcription factor decoys. Current Opinion in Molecular Therapeutics. 1(3): 386-392, 1999
Park YG, Nesterova M, Agrawal S, and Cho-Chung YS: Dual blockade of cyclic AMP response element-(CRE) and AP-1-directed transcription by CRE-transcription factor decoy oligonucleotide: Gene specific inhibition of tumor growth. J. Biol. Chem. 274(3): 1573-1580, 1999

Srivastava RK, Lee YN, Noguchi K, Park YG, Ellis MJC, Jeong JS, Kim SN, and Cho-Chung YS: The RIIb regulatory subunit of protein kinase A binds to cAMP response element: An alternative cAMP signaling pathway. Proc. Natl. Acad. Sci. USA 95(12): 6687-6692, 1998

Srivastava RK, Srivastava AR, Park YG, Agrawal S, and Cho-Chung, YS: Antisense depletion of RIa subunit of protein kinase A induces apoptosis and growth arrest in human breast cancer cells. Breast Cancer Res & Treatment 49: 97-107, 1998

Park YG, Kim MK, Sohn JW, Park GH, and Ryu CK: g-Glutamyltransferase in adult rat hepatocyte during proliferation. Experimental & Molecular Medicine 28: 17-23, 1996

Kim MK, Park YG, Sohn JW, Park GH, and Ryu CK: Application of six monoclonal antibodies in in vitro and in vivo assays to evaluate the tissue specific g-glutamyltransferase. The Korean Journal of Biochemistry 27(2): 105-115, 1995

Kim MK, Park YG, and Ryu CK: Distribution of murine tissue specific g-glutamyltransferase: Comparison of six monoclonal antibody applications in enzyme linked immunosorbent assay, radioimmunoassay, immunohistochemistry, and autoradiography. The Korean Journal of Nuclear Medicine 28(1): 112-123, 1994

Park YG, Ryu CK : Effect of g-glutamyltranspeptidase on rat hepatocyte proliferation. Korea University Medical Journal 29(1): 1-13, 1992

Park YG, Ryu CK : Immunological study of isozyme pattern of gamma-glutamyltransferase from various tissues. Korea University Medical Journal 6(1): 1-9, 1989.

Yim HK, Park YG, Ryu CK : Purification and characterization of gamma-glutamyltransferase of kidney influenced by concurrent occurrence of hepatoma in rat. Korea University Medical Journal 25(1): 353-364, 1988

Lee CN, Park YG, Ryu CK : Characterization of partially purified gamma-glutamyltransferase in hepatocellular carcinoma induced by 2-acetamidofluorene. Korea University Medical Journal 24(3): 177-127, 1987
기타사항(특허, 저서, fellowship, Awards 등)
[저서]
레닌저 생화학 4판(역서), (대표역자) 백형환, 윤경식, Aug 20, 2006, (출판사) 월드사이언스
레닌저 생화학 5판(역서), (대표역자) 백형환, 윤경식, 김호식, March 10, 2010, (출판사) 월드사이언스
하퍼 생화학 28판(역서), (대표역자) 윤경식, 김호식, February 27, 2012, (출판사) 도서출판 M.I.P
하퍼 생화학 29판(역서), (대표역자) 윤경식, 김호식, April 18, 2013, (출판사) 범문에듀케이션
레닌저 생화학 6판(역서), (대표역자) 윤경식, 김호식, February 10, 2014, (출판사) 월드사이언스

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